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ASEA Science – Metabolites (The Movie)

Research conducted by the renowned Human Performance Laboratory at Appalachian State University, validates what ASEA drinkers all around the world already know: ASEA has profound positive benefits to the body. In fact, the research findings were so profound that even the scientists doing the research were astonished by the results.

We blogged about this research over a week ago, but for those of you who prefer to watch the movie rather than read the book, here’s a new video just released where those involved in the research tell the incredible story.


Clinical Trial Shows Athletic Advantage For ASEA Athletes

Study finds that after drinking ASEA for one week, athletes experienced shift in 43 metabolites

Salt Lake City, Utah — ASEA, LLC announces the release of groundbreaking findings at the Experimental Biology 2012 Conference in San Diego of a new study from the Human Performance Laboratory showing increased power output and endurance among competitive athletes.*

David C. NeimanThe study supervised by Dr. David C. Nieman, DrPH, FACSM at the Human Performance Laboratory, Appalachian State University, found that after drinking ASEA athletes experienced massive free-fatty acid mobilization in the blood PRIOR to exercise to a level normally found only after heavy exercise.

“These are very significant findings,” said Nieman. “Our research demonstrated that ASEA is causing mobilization of free-fatty acids PRIOR to exercise, making this source of fuel available at the outset of exercise or competitive performance. This has important implications, especially regarding glycogen sparing, which is something every athlete tries to achieve.”
Glycogen sparing is the use of non-carbohydrates as a source of energy during exercise so that the depletion of muscle glycogen is delayed. When glycogen is spared the body burns fats for energy, making a greater contribution to an athlete’s efforts during the initial stages of a race. This leaves more glycogen for the later stages of racing or exercise, and muscle fatigue will be delayed.

The research found that after drinking ASEA for one week, athletes were experiencing a shift in 43 metabolites.

“We have rarely seen such a drastic difference. For 43 of those signals to change, that is a quarter of the metabolite profile that we are monitoring. It is a huge bump in metabolite shifts that are due to the ingestion of just one product,” said Nieman.

What do these metabolite shifts mean for athletes?

“Athletes actually started the exercise after drinking ASEA with a lot more of these free-fatty acids in their blood. The reason that is important is that the muscles will actually use that as fuel, sparing the muscle glycogen and the use of amino acids which is what we found as we analyzed the data,” said Nieman.

“Every understanding from the literature is that these probably came from the fat stores in the abdominal area,” said Nieman. “So if you drink ASEA we found that the fats go up in the blood. If you’re not exercising, those fats will still be used to support the body’s metabolism for life.”

Simply drinking ASEA for seven days mobilized fuel stores in the body from abdominal fat. For those that want to burn more fat during exercise ASEA is ideal. Even without exercise the freed up fat stores will be used by the body as fuel.

Although this is the first laboratory study of ASEA on athletes, many endurance athletes have been drinking ASEA and noticing improvements in their race times, recovery after racing/training, etc.

James Lawrence, World Record, Most Triathlons 70.3 races, said, “I’ve experienced all these tremendous benefits over the last few years when I’m doing all these world records, and maybe didn’t understand it, but was fearful to go off the product. With this new study it’s really helped me understand why I don’t get sore, and why I’m able to just lock in this strong pace and hold it for so long.”

Cody WaiteCody Waite, professional Xterra triathlete, had this to say about Dr. Nieman’s study. “My thoughts on the study are that I kind of already knew this through my own experience with the product. But at the same time it’s great to have that solid evidence that laboratory test make official. That gives it that official stamp of approval from the scientists and then the stamp of approval from lead athletes.”

Diana Mcmanus Olympic SwimmerDiana MacManus, three-time national swimming champion said, “With ASEA I’ve noticed that my times and my meets have improved significantly. Learning about the research behind ASEA boosts my confidence and reinforces what I already know.” Typically, muscle glycogen is reduced in the body during a single or many groups of energy expenditures. For example, during a single sprint muscle glycogen may deplete by 25% to 30% of the resting levels. Similarly, at the end of longer durations (60 to 90 minutes) of high, moderate and low exercise muscle, glycogen will be dramatically reduced or depleted.

The study included 20 fit athletes in a randomized, double-blind, placebo-based, cross-over study. After baseline testing for VO2Max and body composition, one-half of the athletes drank four ounces of ASEA each day for seven days. The other one-half of the athletes drank four ounces of a placebo for seven days. Then all athletes completed a 75-km cycling trial, with blood drawn prior to the trial, immediately after the trial and one hour after the trial.

After a “washout” period in which none of the athletes drank ASEA or the placebo, a seven day cross-over study was conducted. The original ASEA group drank the placebo and the original placebo group drank ASEA for a seven day period. Then all athletes completed a second 75-km cycling trial, with blood drawn prior to the trial, immediately after the trial and one hour after the trial.

The research demonstrated that drinking ASEA taps into the body’s largest energy reserves, freeing fatty acids from adipose tissue, BEFORE exercise or athletic competition.

“This unexpected mobilization of fatty acids in theory will lead to better endurance in athletes, assisting athletes to maintain a certain pace for longer periods of time,” said Nieman.

The research found that the release of fatty acids is coming from fatty adipose tissue, the body’s source of abundant, available energy. Adipose tissue is fat stored around the organs of the body, with the most common and largest fat store being the abdominal area. Adipose tissue triglycerides represent the largest energy reserve in the human body. Utilizing these stores is critical for prolonged endurance exercise.

The study also demonstrated that the athletes in the study experienced a massive increase in blood levels of ascorbic acid (vitamin C) after exercise. This could indicate less oxidative stress on muscles. Further research is being conducted to determine the implications of this increase.

“This study is the latest in ASEA’s commitment to ongoing research. The frontiers of redox signaling molecules and ASEA are constantly being pushed. This latest study is not a destination, but an on-ramp,” said Verdis Norton, Chief Executive Officer at ASEA.

Human Performance Laboratory

ASU/NCRC Human Performance LaboratoryThe mission of the ASU/NCRC Human Performance Laboratory is to investigate the influence of unique plant molecules (e.g, flavonoids such as quercetin, luteolin, and epigallocatechin 3-gallate or EGCG) on age-related loss of muscle mass (sarcopenia), muscle mitochondrial biogenesis, and exercise-induced changes in immune function, oxidative stress, and inflammation. The Human Performance Laboratory is located at Appalachian State University North Carolina Research Campus and is affiliated with the North Carolina Research Institute which brings together eight universities as well as researchers at Dole, General Foods and Monsanto.

The Company and Product

ASEA, LLC is a Salt Lake City-based company whose flagship product, also called ASEA, is the world’s first and only source of stable, balanced, native-to-the-body Redox Signaling molecules.

ASEA is sold in a 32-ounce bottle and an eight-ounce flexible pouch made from environmentally friendly materials. The 32-ounce bottle is made from a durable plastic. The eight-ounce flexible pouch fits easily into a backpack, pocket or in athletic gear. Both packages were created from input from competitive athletes and everyday ASEA consumers. The eight-ounce pouch includes a one-way valve to keep the pouch contents clean and pure.

ASEA can be purchased through ASEA’s wide network of independent associates.

ASEA and Redox Signaling Molecules

ASEA, with its Redox Signaling technology, is a powerful new drink that helps both competitive and recreational athletes step up their game to new levels of performance.

ASEA is the original and only Redox Signaling product available today. It provides the body with two perfectly balanced sets of reactive molecules — the same molecules produced naturally by the mitochondria in every cell of the body. These vitally important molecules support the production of the ATP energy that fuels our cells, help activate antioxidants, minimize cellular damage, enhance cellular communication, and speed the healing response — all functions critical to athletic performance, endurance and recovery.

Redox Signaling is a burgeoning scientific field on a global scale with an impressive array of recent research advances. Only recently have ASEA scientists been able to produce stable mixtures of these Redox Signaling molecules outside living cells.

ASEA and its foundational technology are completely protected by U.S. patents  5,334,383;  5,507,932;  5,674,537;  5,731,008;  6,007,6866,117,285.

*These statements have not been evaluated by the Food and Drug Administration.  The product is not intended to diagnose, treat, cure or prevent any disease.  The North Carolina Research Institute and its members, including Appalachian State University, do not endorse any products.  The statements by NCRI scientists should not be construed as product promotion.


Patents and Other Goodies for ASEA

We’ve had a number of requests for patent information on the manufacturing, process, and solution known as ASEA.

Currently 6 of the 30 medical and mechanical patents have been approved for use by ASEA and Independent Associates.  ASEA continues to work to obtain the necessary permissions to use additional patents, scientific studies, and research documented since the creation of this product even before it was known as ASEA.

However, this vital information is still tied up in bureaucratic red tape surrounding ASEA’s designation as a supplement rather than a drug.

The original science and research behind the product was done with the intention of creating a new pharmaceutical (drug).  When the original company developing the product ran out of money it was acquired by a biotech company that didn’t really know what it had in regard to the research, manufacturing process, and end product.  So it sold the entire works to Verdis Norton and James Pack, the founders of ASEA.  And, as they say, the rest is history.

Suffice it to say the patents have helped bring another layer of credibility to ASEA and Redox Signaling, the science behind which ASEA is based.

SO…with that the patent numbers are listed below which you can search at to get the detailed patent documents.

  • Category creator, one of a kind product completely protected by more than 30 U.S. patents including patent numbers 5,334,383;  5,507,932;  5,674,537;  5,731,008; 6,007,686;  6,117,285.
  • 17 years and over 20 million dollars spent on research, development, and clinical study.
  • The world’s first and only Redox Signaling Supplement – Redox Signaling Molecules are Native to the body – Required by every BODY.
  • Company is less than 2 years old yet was profitable in its first year in an industry where 90% of start-up companies fail in their first year.
  • Company on track to double revenue in 2012.
  • Athletic performance and endurance benefit is driving the company to worldwide distribution. Once an athlete learns the advantage this product provides they will not be without it

Clinical studies:

  • Safe for ingestion and exhibits zero toxicity, based on standard safety biomarkers.
  • Athletic endurance, as measured by time to ventilatory threshold and time to VO2max , is significantly increased by more than 10% on average.
  • Helps speed recovery after athletic exertion.

Claims Supported by Research Institutions

  • Increases antioxidant efficiency of glutathione peroxidase and superoxide dismutase (SOD) inside living cells more than 500%.
  • Significantly stimulates the production of the master antioxidants inside the cells without causing an inflammatory response.
  • Significantly increases the efficiency of communication signals between cells, those involved in cell damage detection, cell repair, and cell replacement.

Product specific facts:

  • The only stable perfectly balanced mixture of reactive molecules that exist outside of the body.
  • The product of more than 16 years of research, showing it to be a safe and natural way to help your body function as it should.
  • The product components are native to the body and consistent with its natural chemical balance.
  • Supports immune system functions that reduce oxidative stress and repair cellular damage.
  • Accelerates the body’ production of its own natural antioxidants, like glutathione, superoxide dismutase (SOD), and catalase.
  • The only product that delivers the balanced foundation that every person must have to allow their body and immune system to function at the cellular level.

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Breakthrough should equal One of a Kind

Today, it can be hard to get excited about a breakthrough. That’s because everything is called a “breakthrough.” There’s always something new and exciting popping up around us. So when someone says they’ve made a breakthrough, it just gets lost in background noise, where it typically belongs.

Unless, of course, it actually is something that hasn’t been done before. Ever.

That’s ASEA.

Sixteen years of foundational research led to the creation of the first and only perfectly balanced mixture of stabilized Redox Signaling molecules that exists outside the body. In case you haven’t heard of Redox Signaling molecules, they’re what your body creates to support the vital functions of the immune system. They’re so important that the body manufactures its own supply within the cells.

One set of these molecules is responsible for activating antioxidants. Here’s the deal: no matter how many antioxidants you ingest, they can’t fight even one free radical until they’re activated, so these molecules are important. The other set of molecules are essential for cellular communication, cellular protection, and the healing response.

So it’s easy to see why your own body makes these molecules. And until now, the body was the only source. But today there’s one more: ASEA.

Want to chat about Asea? Have more questions than are answered in this blog?

Contact Us, we’d love to visit with you!


New Discovery ~ New Breakthrough ~ New Science

Video Transcript:

My Name is Ronald V Norris M.D. I am from Boston Massachusetts. Dr John Baird Louisville Kentucky. I’m Shelly Roby from Elizabethtown Kentucky. I’m Dr. Rob Ward, I am a family Practitioner. Gary Samuelson, I’m an Atomic Physicist. My name is Dave Carpenter I am a Naturopathic Medical Doctor.

“Our Cells Age with us, part of the disease process is actually that your cells get damaged” – Dr John Baird

“As we age the healing process becomes a little bit more slow, less efficient.” – Dr. Gary Samuelson Atomic Physicist.

“We have to find a way to have those cell rejuvenated.” – Dr. John Baird

“In our cells we all have mitochondria. What the mitochondria do, that is the energy generating factory in our cell. As part of that process their are molecules that are produced as by products. These molecules are called reactive oxygen species. These are molecules that make up the redox signaling system. What’s important is that they be balanced. Depending on our health circumstance we can produce more or less of those molecules, when they are not balanced these become dangerous to the cell. They produce these little molecules that don’t have a paired electron around their nucleus. When they have to be neutralized that’s done by antioxidants. Well those antioxidants can’t work unless they become activated by this redox signaling system.” – Ronald V Norris M.D.

“Redox Signaling molecules are absolutely crucial to maintaining peak efficiency in cell function.” – Dr. Rob Ward

“It’s all about Homeostatis and balance and what it does is allow your body to perform at it’s maximum at it’s best level by balancing things at the cellular level. ” – Shelly Roby

“This is a remarkable process, because it is actually the process which allows us to regenerate tissue and maintain our health.” – Gary Samuelson

“ASEA doesnt’ cure anything, but it does go into your cells that aren’t function properly and enable them to work better.” – Dr. John Baird

“As we age we just don’t produce enough of these molecules to maintain balance in our body. ASEA is providing that.” – Dr. Rob Ward

“What I believe is ground breaking is that we have been able to stabilize certain mixtures of redox signaling molecules so that they can be effectively stored outside the body.” – Dr. Gary Samuelson, Atomic Physicist

“The beauty of ASEA is that it helps support the cell so well that one doesn’t have to take as many other supplements. You just take less supplements and get the same result because the cell is so much more efficient.” – Dave Carpenter, Naturopathic M.D.

“It enables you to go into your cells, repair whatever cell damage has been done, make them work better. And then if you add exercise and diet on to that you will be even healthier.” – Dr John Baird.

“Everything started making sense, I started connecting the dots. Yeah I wanted to use this product, because at the age of 55 my cell efficiency has dwindled. I was curious to see what my body would be capable of doing. It occurred to me, hey why not. Especially if I am going to have an interest in perhaps sharing this with others. I need to be able to say how this has helped me” – Dr Rob Ward

“I also noticed when I was working out a more significant amount of energy and longer endurance. I really felt like I was 20, 25 years younger. It was incredible.” Dr. Dave Carpenter

“I found that I experienced increased mental clarity, increased energy” – Ronald V. Norris M.D.

“One of the great benefits that redox signaling can have for us is that it helps accelerate and maintain healthy tissue.” – Dr. Gary Samuelson, Atomic Physicist

“I am so excited about this new awareness, this new paradigm of what we can do with our health” – Dr. Rob Ward

“I feel very confident giving this to all of my patients. It’s something they need, it’s something that their cells lack. We are just restoring it because it is native to the body, it’s already there just not enough of it.” – Dr. Dave Carpenter

“Every patient that I see I share ASEA with and my story, my experience with ASEA.” – Shelly Roby

“This technology has the potential of spear heading some of the greatest advances of health, in the world.” Dr. Gary Samuelson

“The thing I like about ASEA is that it is very scientifically backed.” – Dr. Dave Carpenter

“So, just in the same way your mom used to try to give you something that you really would need to help you get well, ASEA is providing a balance just like your moms chicken noodle soup.” – Dr. Rob Ward

“The possibility of being able to stabilize redox signaling molecules and use them as bio-active non-toxic agents inside our body is phenomenal. It will make a difference, and it will be the future technology that will affect almost all areas of health science and well being.” – Dr Gary Samuelson, Atomic Physicist.

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